Generalversammlung SGH

Symposium SGH Teil 1

Myeloproliferative Neoplasms in 2009
Chairpersons: André Tichelli, Basel / Andreas Tobler, Bern

20 years of Interferon therapy for Ph-negative myeloproliferative disorders: from hematological to molecular response
Jean-Jacques Kiladjian, Bobigny FR

Vorträge der Preisträger

Preis für klinische Hämatologie
Abstract No. SGH 1
Jakob Passweg, Genève

Preis für experimentelle Hämatologie
Abstract No. SGH 2
Nicolas Bonadies, Cambridge GB

Preisverleihung des Roche Hämostase-Preises und Vortrag des Preisträgers

Symposium SGH Teil 2

Iron and Anemia
Chairpersons: Jean-Philippe Grob, Lausanne / Ulrich Buser, Basel

Iron deficiency anemia in the light of recent findings in iron metabolism

Photis Beris, Genève

Anemia of chronic disease

Sigismond Lasocki, Paris FR

Anemia in the elderly

Elizabeth A. Price, Palo Alto US

Experimental Hematology

Chairpersons: Olivier Spertini, Lausanne / Martin Fey, Bern

Donor T Cell Production of IL-21 Accelerates Graft-Versus-Host Disease Lethality

Bucher C., Vogtenhuber C., Jasperson L., Goren E., Panoskaltsis-Mortari A., Sivakumar P., Blazar B. (Minneapolis, Seattle)

Large-scale clinical grade expansion of alloreactive haploidentical natural killer cells for multiple infusions to leukemia patients

Siegler U., Meyer-Monard S., Jörger S., Stern M., Tichelli A., Gratwohl A., Wodnar-Filipowicz A. (Basel)

Involvement of microRNAs in post-transcriptional regulation of NKG2D ligand expression in human tumor cell lines

Himmelreich H., Mathys A., Wodnar-Filipowicz A., Kalberer C. (Basel)

HUMAN EMBRYONIC STEM CELLS DIFFERENTIATED IN ABSENCE OF XENOGENIC COMPOUNDS GENERATE CD34+ AND CD34- HEMATOPOIETIC CELLS WITH DISTINCT PROGENITOR CHARACTERISTICS

Chicha L., Jaconi M., Passweg J., Kindler V. ( Geneva)

Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as essential regulator of SDF1α/CXCR4-mediated homing and migration

Schwaller J., Brault L., Grundler R., Gasser C., Bullock A., Ehret S., Woetzel S., Berridge G., Spoo A., Dierks C., Biondi A., Knapp S., Schwaller J. (Basel, München, Oxford, Freiburg/Breisgau, Monza)

The fusion protein PML-RARA suppresses the master transcription factor PU.1 by targeting the chaperone protein calreticulin.

Vallabhapurapu D., Christen E., Petkovic V., Schardt J., Pabst T., Mueller B.U. (Bern)

Protein disulfide isomerase (PDI) is upregulated during the unfolded protein response and blocks CEBPA mRNA translation in leukemic cells.

Pabst T., Haefliger S., Eyholzer M., Timchenko N., Mueller B., Pabst T. (Bern, Houston,TX)

Myeloid differentiation of leukemic cells critically depends on autophagy

Britschgi A., Yousefi S., Simon H.U., Tobler A., Fey M.F., Tschan M.P. (Bern)

A MOUSE MODEL FOR TESTING THE EFFICACY OF JAK2 INHIBITORS

Kubovcakova L., Hao-Shen H., Looser R., Pianta A., Schaub F., Lundberg P., Skoda R.C. (4031, Basel)

Disruption of GAS6-MER Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages

Kadi l., Burnier L., Rocco S., Carmeliet P., Lemke G., Earp S., Matsushima G., Schapira M. (Lausanne, Belgium, USA

Freie Mitteilungen SGH 2

Hemostasis, Vascular Biology and Transfusion Medicine

Chairpersons: Behrouz Mansouri, Bern / Anne Angelillo-Scherrer, Lausanne

Erythrocytes from hyperlipemic donors have a higher rate of hemolysis after storage

Schulzki T., Reinhart W. (Chur)   

Diagnostic value of platelet flow-cytometric analysis in patients with clinically relevant bleeding diathesis and unrevealing laboratory work-up

Alberio L., Conte T., Pavicic M., Reusser M., Barizzi G., Keller P. (Bern)    

Vinorelbine and Pegfilgrastim for Mobilization of Peripheral Blood Progenitor Cells in Patients with Multiple Myeloma: A Predictive and Cost Effective Procedure

Bargetzi M., Pabst T., Schoenenberger A., Burger J., Fernandez P., Moosmann P., Mansouri B., Huber A., Baerlocher G., Wernli M., Heizmann M. (Aarau, Bern)    

Massively Reduced Arachidonic Acid in Red Cell Membranes and in Adipose Tissues with a Diet Rich in Alpha-Linolenic Acid which Diminishes Atherosclerosis in Apolipoprotein E-Deficient Mice

Beer J.H., Matter C., Lohmann , Richter , Leiber , Tanner F., Lüscher T. (Baden, Zürich)    

The Gain of Function Platelet Polymorphism of GPIb alpha (5T/C) is Overrepresented in Smokers with Symptomatic Carotid Stenosis: An Exploratory Study

Beer J.H., Lugli-Kopp , Brown M., Steffel , Büchi , Spleiss , Förnzler , Dupont , Gaussem , Forestier (Baden, London, Basel, Paris)    

Klinische Fassetten des hereditären Angioödems (HAE) bei einem Schweizer Patientenkollektiv

Wuillemin W.A., Wuillemin W.A. (Luzern)    

GENERATION AND PHENOTYPIC ANALYSIS OF PROTEIN S-DEFICIENT MICE

Saller F., Brisset A.C., Azevedo M., Chrast R., Schapira M., Griffin J.H., Angelillo-Scherrer A. (Lausanne, Service and Central Laboratory of Hematology, CHUV, Lausanne, Department of Medical Genetics, UNIL, Lausanne, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, USA)    

Pharmacokinetics of dalteparin in therapeutic dosage in patients with renal insufficiency

Schmid P., Brodmann D., Odermatt Y., Fischer A.G., Wuillemin W.A. (Luzern)    

Congenital or acquired ADAMTS13 deficiency or both – that’s the question.

Meyer S.C., Sulzer I., Mäder G., George J.N., Lämmle B., Kremer Hovinga J.A. (Bern, Oklahoma City)

Clinical Hematology

Chairpersons: Jakob Passweg, Genève / Urs Schanz, Zürich

25 years of stem cell transplantation in Geneva. Impact of immunotherapy using donor derived T-cells. Review and Outlook

Chalandon Y., Roosnek E., Helg C., Kindler V., Huguet S., Mohty B., Mach-Pascual S., Ansari M., Tiercy J.M., Miralbell R., Chapuis B., Passweg J. (Genève)

Late Altered Organ Function in Long Term Survivors after Allogeneic HSCT: A Paired Comparison with their Identical Sibling Donor.

Rovo A., Daikeler T., Halter J., Heim D., Studt J.D., lMedinger M., Arber C., Stern M., Tsakiris D., Tyndall A., Gratwohl A., Tichelli A. (Basel)

“Late altered immunity” a distinct entity in long term survivors after allogeneic HSCT?

Rovo A., Daikeler T., Halter J., Heijnen I., Heim D., Arber C., Tyndall A., Gratwohl A., Tichelli A. (Basel)

Severe immune hemolysis and pure red cell aplasia after haploidentical nonmyeloablative allogeneic stem cell transplantation

Nair G., Mischo A., Stussi G., Schanz U. (Zürich)

Rituximab for chronic Graft-versus-host disease

Nair G., Schanz U., Stussi G. (Zürich)

THE ABUNDANT CD56bright NK-CELL POPULATION AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) ARE CYTOKINE ACTIVATED- RATHER THAN IMMATURE NATURAL KILLER CELLS

Vukicevic M., Chalandon Y., Helg C., Matthes T., Dantin C., Huard B., Passweg J., Roosnek E. (Genève)

Prospective registration and follow up of donors of allogeneic hematopoietic stem cells (HSC) in a common protocol for related and unrelated donors: experience of the first 18 month

Halter J., Nicoloso-de Faveri G., Buhrfeind E., Baldomero H., Chalandon Y., Huguet S., Stüssi G., Güngör T., Seger , Passweg J., Schanz U., Gratwohl A. (Basel, Bern, Genève, Zürich)

First Results of the GRAAPH-2005 Study in younger Adult Patients with De Novo Philadelphia Positive Acute Lymphoblastic Leukemia

Chalandon Y., Thomas X., Hayette S., Cayuela J.M., Abbal C., Escoffre-Barbe M., Maury S., Lepretre S., Witz F., Malfuson J.V., Leguay T., Buzyn A., Dombret H. (Genève, GRAALL group Lyon France, GRAAL group Lyon France, Hôptital Saint Louis, Paris, France, CHUV, Lausanne, Hôpital Ponchaillou, Rennes, GRAAL group, Lyon, France, Hôpitaux de Brabois, Nancy, France, CHU de Bordeaux, France)

Investigating acute leukemias with gene expression arrays in a routine setting: a pilot study from the Geneva University Hospital

Matthes T., Rossier M., Rebsamen M., Chiappe A., Diemand A., Schindela S., Johnson A., Liu W.m., Wieczorek L., Haferlach T., Kohlmann A. (Genève, Munich, Pleasanton)

Acute lymphoblastic leukemia in childhood: proliferation at different stages of immunophenotypic maturation

Hirt A., Schmid A.M., Leibundgut K. (Bern)

Platelet transfusion threshold for central venous catheter insertion in patients with hematological malignancies

Zeidler K., Arn K., Senn O., Schanz U., Stüssi G. (Münsterlingen, Zürich)

Divisional Heterogeneity in Long-Term Hematopoietic Stem Cells

Takizawa H., Boddupalli S., Manz M. (Bellinzona)

Increased somatic mutation rate in hematopoietic cells from MPD patients is detectable prior to the acquisition of the JAK2-V617F mutation

Lundberg P., Skoda R., Rischewski J., Tichelli A. (Basel)

The first case of IRIDA in Switzerland: characterisation of two novel mutations and successful treatment by continuous i.v. iron infusion.

Tchou I., Diepold M., Villard J., Swinkels D., Neerman-Arbez M., Beris P. (Dep. of Internal Medicine, HUG, Geneva, Pediatric Clinic, Bern Univ. Hospital, Radboud Universiteit Nijmegen, NL, Medical Genetics, CMU-Geneva)